84-4359-28 p62Dok, phosphorylated (Tyr398) 100ul 327271
特徴
- DOK proteins are enzymatically inert adaptor or scaffolding proteins.
- They provide a docking platform for the assembly of multimolecular signaling complexes.
- DOK1 appears to be a negative regulator of the insulin signaling pathway.
- Modulates integrin activation by competing with talin for the same binding site on ITGB3.
- Michael J.
- Wick, et al.
- (2001) J.
- Biol.
- Chem ; 276: 42843 - 42850.
- Paul D.
- Simoncic, et al.
- (2006) Mol.
- Cell.
- Biol ; 26: 4149 - 4160.
- Nadia Dub
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of tyrosine 398 (E-G-Y(p)-E-L) derived from human p62Dok.
- Shelf Life：1year
- Swiss Prot Number：Q99704
- EU Commodity Code：30021010
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- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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