One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Joell L.
Solan1, et al.
(2003) Cell Science 116: 2203-2211 Satoshi Matsushita, et al.
(2006) Histochemistry and Cytochemistry 54 (3): 343-353, Xiaoyong Bao, et al.
(2004) Cell Physiol 286: C647-C654 W.
E.
I.
Li, et al.(1998) European Journal of Neuroscience 10: 2444
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity:Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Peptide corresponding to the sequence around phosphorylation site of serine 368(R-A-S(p)-S-R) derived from human Connexin 43.