84-4359-06 p27Kip1(Phospho-Thr187) 100ul 327140
特徴
- Important regulator of cell cycle progression.
- Involved in G1 arrest.
- Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes.
- Positive regulator of cyclin D-dependent kinases such as CDK4.
- Regulated by phosphorylation and degradation events.
- Eguchi H, et al.
- (2003) Cancer Res; 63(15): 4739-46 Le XF, et al.
- (2003) J Biol Chem; Connor MK, et al.
- (2003)
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of threonine 187 (E-Q-T(p)-P-K) derived from human p27Kip1.
- Shelf Life：1year
- Swiss Prot Number：P46527
- EU Commodity Code：30021010
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