84-4358-96 ASK1(phosphorylated Ser966) 100ul 306978
特徴
- Component of a protein kinase signal transduction cascade.
- Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively.
- Overexpression induces apoptotic cell death.
- Zhang W, et al.
- (2005) J Biol Chem.
- 280(19): 19036-19044.
- Fujii K, et al.
- (2004) Oncogene.
- 23(29):5099-5104.
- Goldman EH, et al.
- (2004) J Biol Chem 2004 Mar 12; 279(11): 10442-10449.
- Zhang L, et al.
- (1999) Proc Natl Acad Sci U S A.
- 96(15): 8511-8515.
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human Mouse Monkey
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mk Mo
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of serine 966 (S-I-S(p)-L-P) derived from human ASK1.
- Shelf Life：1year
- Swiss Prot Number：Q99683
- EU Commodity Code：30021010
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- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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