YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection.
Binds and stabilizes cytoplasmic mRNA.
Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes.
Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs).
Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL.
Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B.
Homodimer in the presence of ATP.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Peptide corresponding to the sequence around phosphorylation site of Serine 102(L-R-S(p)-V-G) derived from Human YB1.
