84-4357-07 ［取扱停止］Nuclear Receptor NR4A1 (phosphorylated Ser351) 100ul 326435
特徴
- Orphan nuclear receptor.
- May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.
- Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'.
- May inhibit NF-kappa-B transactivation of IL2.
- Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Nakai A., Mol.
- Endocrinol.
- 4:1438-1443(1990).
- Chang C., J.
- Steroid Biochem.
- 34:391-395(1989).
- Bondy G.P., Cell Growth Differ.
- 2:203-208(1991)
- Applications:Suitable for use in Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IHC
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of Serine351(L-P-S(p)-K-P) derived from Human Nuclear Receptor NR4A1.
- Shelf Life：1year
- Swiss Prot Number：P22736
- EU Commodity Code：30021010
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