84-4356-76 Cyclin D1 (phosphorylated Ser90) 100ul 312477
特徴
- Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
- In vitro catalyzes 'Lys-48'-linked polyubiquitination.
- Mediates the selective degradation of short-lived and abnormal proteins.
- Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
- Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1.
- Ubiquitinates STUB1-associated HSP90AB1 in vitro.
- Lacks inherent specificity for any particular lysine residue of ubiquitin.
- Essential for viral activation of IRF3.
- Mediates polyubiquitination of CYP3A4.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of serine 90(F-L-S(p)-L-E) derived from Human Cyclin D1 .
- Shelf Life：1year
- Swiss Prot Number：P24385
- EU Commodity Code：30021010
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