84-4356-07 Trk A (Phospho-Tyr680/681) 100ul 338193
特徴
- Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF).
- Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1.
- Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating.
- Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around phosphorylation site of tyrosine 680/tyrosine 681 (T-D-Y(p)-Y(p)-R-V) derived from Human Trk A.
- Shelf Life：1year
- Swiss Prot Number：P04629
- EU Commodity Code：30021010
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