84-4355-05　Ephrin-B2(Phospho-Tyr330) 100ul　315011

特徴

• Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma).
• Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure.
• a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
• a- and gamma-adducins are ubiquitously expressed.
• In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues.
• Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
• Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
• Chrencik JE,et al.( 2006) J Biol Chem;281(38):28185-28192.
• Kertesz N, et al.
• (2006) Blood; 107(6):2330-2338.
• Noren NK, et al.
• (2004) Proc Natl Acad Sci USA; 101(15):5583-5588.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.