84-4352-92 Patched 100ul 327580
特徴
- Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH).
- Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal.
- Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.Trudy G.
- Oliver, Development, May 2005; 132: 2425 - 2439.
- Florence Brellier, Cancer Res., Apr 2004; 64: 2699 - 2704.
- Heidi Hahn, J.
- Biol.
- Chem., May 1996; 271: 12125.
- RL Johnson, Development, Dec 1995; 121: 4161.
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human Mouse
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide corresponding to human Patched.
- Shelf Life：1year
- Swiss Prot Number：Q13635
- EU Commodity Code：30021010
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