84-4352-25 Nuclear Receptor NR4A1 (Ab-351) 100ul 326434
特徴
- Orphan nuclear receptor.
- May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.
- Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity.
- May inhibit NF-kappa-B transactivation of IL2.
- Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Nakai A., Mol.
- Endocrinol.
- 4:1438-1443(1990).
- Chang C., J.
- Steroid Biochem.
- 34:391-395(1989).
- The MGC Project Team; Genome Res.
- 14:2121-2127(2004).
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity:Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthesized non-phosphopeptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P).
- Shelf Life:1year
- Swiss Prot Number:P22736
- EU Commodity Code:30021010
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