84-4351-83 PKCd 100ul 329757
特徴
- This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
- PKC is activated by diacylglycerol.
- which in turn phosphorylates a range of cellular proteins.
- PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
- May play a role in antigen-dependent control of B-cell function.
- Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
- Kei Sakamoto, et,al.
- (2003) Am J Physiol Endocrinol Metab, ; 285: E1081 - E1088.
- Ling Zhang, et,al.
- (2004) J.
- Biol.
- Chem ; 279: 28315 - 28319.
- Kristof Van Kolen et,al.
- (2006) FEBS J ; 273: 1843 - 1854.
- Martin Villalba, et,al.
- (2002) J.
- Cell Biol ; 157: 253.
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IF WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around aa643-647 (R-L-S-Y-S) derived from Human PKCd.
- Shelf Life：1year
- Swiss Prot Number：Q05655
- EU Commodity Code：30021010
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
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