84-4351-77 p62Dok 100ul 327269
特徴
- DOK proteins are enzymatically inert adaptor or scaffolding proteins.
- They provide a docking platform for the assembly of multimolecular signaling complexes.
- DOK1 appears to be a negative regulator of the insulin signaling pathway.
- Modulates integrin activation by competing with talin for the same binding site on ITGB3.
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IF WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around aa396-400 (P-I-Y-D-E) derived from Human p62Dok.
- Shelf Life：1year
- Swiss Prot Number：Q99704
- EU Commodity Code：30021010
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