84-4351-55 ASK1(Ab-83) 100ul 306975
特徴
- Component of a protein kinase signal transduction cascade.
- Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively.
- Overexpression induces apoptotic cell death.
- Mabuchi S, et al.
- (2004) Endocrinology.
- 145(1): 49-58.
- Yuan ZQ, et al.
- (2003) J Biol Chem.
- 278(26): 23432-23440.
- Kim AH, et al.
- (2001) Mol Cell Biol.
- 21(3): 893-901.
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity:Human
- Isotype:IgG
- Calc Applications Abbrev:IF WB
- Calc Crossreactivity:Hu
- Immunogen:Peptide corresponding to the sequence around aa81-85 (G-S-S-V-G) derived from Human ASK1.
- Shelf Life:1year
- Swiss Prot Number:Q99683
- EU Commodity Code:30021010
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