84-4350-05 CBR1 100ul 309472
特徴
- NADPH-dependent reductase with broad substrate specificity.
- Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics.
- Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.
- Can convert prostaglandin E2 to prostaglandin F2-alpha.
- Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.
- Catalyzes the reduction of S-nitrosoglutathione.Wermuth B., J.
- Biol.
- Chem.
- 263:16185-16188(1988).
- Forrest G.L., Biochim.
- Biophys.
- Acta 1048:149-155(1990).
- Forrest G.L., Mol.
- Pharmacol.
- 40:502-507(1991).
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to internal of human CBR1.
- Shelf Life：1year
- Swiss Prot Number：P16152 Gene ID: 873
- EU Commodity Code：30021010
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