84-4349-24 Cytochrome P450 2C8 100ul 312855
特徴
- Cytochromes P450 are a group of heme-thiolate monooxygenases.
- In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.
- It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
- In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids.
- It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).Romkes M., Biochemistry 30:3247-3255(1991).
- Ged C., Biochim.
- Biophys.
- Acta 1088:433-435(1991).
- Zeldin D.C., Arch.
- Biochem.
- Biophys.
- 322:76-86(1995).
-
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to internal of human Cytochrome P450 2C8.
- Shelf Life：1year
- Swiss Prot Number：P10632
- EU Commodity Code：30021010
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