Plays an adhesive role by integrating collagen bundles.
It is probably associated with the surface of interstitial collagen fibrils via COL1.
The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors By similarity.Nusbaum C., Nature 439:331-335(2006).
Bauer M., Biochim.
Biophys.
Acta 1354:183-188(1997).
Just M., J.
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Chem.
266:17326-17332(1991).
Applications:Suitable for use in Immunofluorescence and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity:Human Mouse
Isotype:IgG
Calc Applications Abbrev:IF IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to internal of human Collagen XIV alpha1.