84-4347-98 ATF1 100ul 307060
特徴
- This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters.
- Binds to the Tax-responsive element (TRE) of HTLV-I.
- Mediates PKA-induced stimulation of CRE-reporter genes.
- Represses the expression of FTH1 and other antioxidant detoxification genes.
- Triggers cell proliferation and transformation.Yoshimura T., EMBO J.
- 9:2537-2542(1990).
- Rehfuss R.P., J.
- Biol.
- Chem.
- 266:18431-18434(1991).
- Hai T., Genes Dev.
- 3:2083-2090(1989).
- Applications:Suitable for use in Immunofluorescence and Western Blot.
- Other applications not tested.
- Recommended Dilution:Immunofluorescence: 1:100-1:500Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity:Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:IF WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to internal of human ATF1.
- Shelf Life:1year
- Swiss Prot Number:P18846 Gene ID: 466
- EU Commodity Code:30021010
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