84-4347-62　PDZD2 (PDZK3, AIPC, KIAA0300, PDZ domain-containing protein 2, Activated in prostate cancer protein, PDZ domain-containing protein 3) 100ul　327831

特徴

• Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels.
• They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling.
• The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16).
• Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains.
• In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
• Applications:Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.