84-4346-65 TOP2A (Ab-1343) 100ul 337580
特徴
- Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.
- Topoisomerase II makes double-strand breaks.
- Essential during mitosis and meiosis for proper segregation of daughter chromosomes.Tsai-Pflugfelder M., Proc.
- Natl.
- Acad.
- Sci.
- U.S.A.
- 85:7177-7181(1988).
- Wasserman R.A., Cancer Res.
- 53:3591-3596(1993).
- Lang A.J., Gene 221:255-266(1998).
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthesized non-phosphopeptide derived from human TOP2A around the phosphorylation site of threonine 1343 (E-K-T(p)-D-D).
- Shelf Life：1year
- Swiss Prot Number：P11388 Gene ID: 7153
- EU Commodity Code：30021010
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