84-4346-08 IGF-1R(Ab-1346) 100ul 319968
特徴
- This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity.
- It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade.
- When present in a hybrid receptor with INSR, binds IGF1.
- Adams, T.E.
- et al.
- (2000) Cell.
- Mol.
- Life Sci.
- 57, 1050-1093 Baserga, R.
- et al.
- (2000) Oncogene 19, 5574-5581 Scheidegger, K.J.
- et al.
- (2000) J.
- Biol.
- Chem.
- 275, 38921-38928.
- O'Connor R, et al.
- Mol Cell Biol 1997 Jan; 17(1): 427-35
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Species Crossreactivity: mouse and rat
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo Rt
- Immunogen：Peptide corresponding to the sequence around aa1344-1348 (Q-P-Y-A-H) derived from human IGF-1R .
- Shelf Life：1year
- Swiss Prot Number：P08069
- EU Commodity Code：30021010
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