84-4345-86 eIF4B(Ab-422) 100ul 314592
特徴
- Required for the binding of mRNA to ribosomes.
- Functions in close association with EIF4-F and EIF4-A.
- Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP.
- Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
- Gingras, A.C.
- et al.
- (2001) Genes Dev.
- 15, 807-826.
- Duncan, R.
- and Hershey, J.W.
- (1985) J.
- Biol.
- Chem.
- 260, 5493-5497.
- Duncan, R.F.
- and Hershey, J.W.
- (1989) J.
- Cell Biol.
- 109, 1467-1481.
- Applications:Suitable for use in Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human Mouse
- Isotype：IgG
- Calc Applications Abbrev：IHC WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Peptide corresponding to the sequence around aa420-424 (T-G-S-E-S) derived from human eIF4B.
- Shelf Life：1year
- Swiss Prot Number：P23588 Protein: NP_001408.2
- EU Commodity Code：30021010
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