Plays a key role in the control of the eukaryotic cell cycle.
It is required in higher cells for entry into S-phase and mitosis.
p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Ukomadu C, et al.(2003) J Biol Chem; 278(7): 4840-6 Morris MC, et al.(2002)J Biol Chem; 277(26): 23847-53 Brown NR, et al.(1999)J Biol Chem; 274(13): 8746-56 Liu Y, et al.(2004) J Biol Chem; 279(6): 4507-14
Applications:Suitable for use in Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity:Species Crossreactivity: mouse and rat
Isotype:IgG
Calc Applications Abbrev:IF WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Peptide corresponding to the sequence around aa159-163 (T-Y-T-H-E) derived from human CDC2.