Interacts with the internal control region (ICR) of ~50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III.
Also binds the transcribed 5S RNA's.
May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes.Arakawa H., Cytogenet.
Cell Genet.
70:235-238(1995).
Dunham A., Nature 428:522-528(2004).
Drew P.D., Gene 159:215-218(1995).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to Internal of human GTF3A.