84-4342-25　UBASH3A (Ubiquitin-Associated and SH3 Domain-Containing Protein A, Cbl-interacting Protein 4, CLIP4, Suppressor of T-Cell Receptor Signaling 2, STS-2, T-Cell Ubiquitin Ligand 1, TULA-1, TULA1, STS2) 100ul　338751

特徴

• Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases.
• Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
• Exhibits negligigle protein tyrosine phosphatase activity at neutral pH.
• May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation.
• May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.