84-4342-22 SRSF7 (9G8, SFRS7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, Arginine/serine-rich 7) 100ul 334065
特徴
- Required for pre-mRNA splicing.
- Can also modulate alternative splicing in vitro.
- Represses the splicing of MAPT/Tau exon 10.
- May function as export adapter involved in mRNA nuclear export such as of histone H2A.
- Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity.
- RNA-binding is semi-sequence specific.Cavaloc Y., EMBO J.
- 13:2639-2649(1994).
- Popielarz M., J.
- Biol.
- Chem.
- 270:17830-17835(1995).
- The MGC Project Team, Genome Res.
- 14:2121-2127(2004).
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
- Specificity：Human Mouse
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide corresponding to internal of human SFRS7.
- Shelf Life：1year
- Swiss Prot Number：Q16629
- EU Commodity Code：30021010
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