Acts as a regulator of endocytic traffic by participating in membrane delivery.
Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis.
Also required for the structural integrity of the endosomal recycling compartment during interphase.
May play a role in breast cancer cell motility by regulating actin cytoskeleton.Prekeris R., J.
Biol.
Chem.
276:38966-38970(2001).Ishikawa K., DNA Res.
5:169-176(1998).Daniels R.J., Hum.
Mol.
Genet.
10:339-352(2001).
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Human Mouse
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to C-terminal of human RAB11FIP3.
