Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs).
Elongates C24:0 and C26:0 acyl-CoAs.
Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum.
May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps.
May play a critical role in early brain and skin development.Zhang K., Nat.
Genet.
27:89-93(2001).
Edwards A.O., Invest.
Ophthalmol.
Vis.
Sci.
42:2652-2663(2001).
Ota T., Nat.
Genet.
36:40-45(2004).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Human Mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to internal of human ELOVL4.
