Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading.
Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.
Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT.
Plays a role in the regulation of mast cell degranulation.
Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling.
Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR.
Phosphorylates BCR and down-regulates BCR kinase activity.
Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Human Mouse
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to internal of human FES.
