VMP1 (Vacuole membrane protein 1), is a 406aa multi-pass membrane protein that localizes to the endoplasmic reticulum-golgi intermediate compartment membrane.
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death.
May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.
Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity).
Involved in cell-cell adhesion.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Western Blot: 1:200-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity:Species Crossreactivity: mouse and rat