SH2D3A (SH2 domain containing 3A), also known as novel SH2-containing protein 1, is a 576aa protein that is thought to play a role in JNK activation.
SH2D3A interacts with p130 Cas and is found at low levels in fetal kidney, fetal lung, placenta, adult pancreas, kidney and lung.
Subject to post-translational phosphorylation on multiple tyrosine residues, SH2D3A contains one Src homology 2 (SH2) domain.
SH2 domains bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
