PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors.
PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins.
It is a multi-domain protein with strong transcriptional repression properties.
PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland.
Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer.
PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:10,000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
