The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members.
FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type.
They form 14-15kD proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids.
They may also be responsible in the modulation of cell growth and proliferation.
Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells.
This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele.
Thr-54 protein is associated with increased fat oxidation and insulin resistance.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity:Recognizes human FABP2. Species Crossreactivity: mouse and rat