This gene encodes a protein that is a member of the integrin superfamily.
Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell.
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion.
Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches.
Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule.
Alternate splicing results in multiple transcript variants.
Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:10,000Western Blot: 1:200-1:1000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
