Exendin 4 is a 39aa peptide found in venom from the Gila monster Helicoderma suspectum.
It is a member of the glucagon secretin family of peptide hormones and neuropeptides.
Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion.
It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation.
It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying.
Interacts with GLP-1 receptor (GLP1R).
Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions:ELISA: 1:1000-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
