ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193aa protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation.
In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells.
The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene.
Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
