Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52aa, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide.
It may function as a hormone in circulation control because it is found in blood in a considerable concentration.
The precursor, called preproadrenomedullin, is 185aa long.
By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues.
Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.
There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Immunohistochemistry: 1:15-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Recognizes human Adrenomedullin. Species Crossreactivity: rat
