This gene was identified as a retinoid acid (RA) receptor-responsive gene.
It encodes a type 1 membrane protein.
The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors.
The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island.
Alternatively spliced transcript variant encoding distinct isoforms have been observed.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:500-1:2000Immunohistochemistry: 1:100-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.