This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB).
The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function.
The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes.
This gene encodes the p100 subunit that is processed into the active p52 subunit.
This protein can function as both a transcriptional activator and repressor, depending on its dimer partner.
Alternate splicing results in both coding and non-coding variants.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:10,000Western Blot: 1:1000-1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.