At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.
The protein encoded by this gene binds DNA and is a component of heterochromatin.
This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane.
The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
This protein binds histone H3 tails methylated at Lys-9 sites.
This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.