84-4265-89 FOXL2 100ul 316350
特徴
- This gene encodes a forkhead transcription factor.
- The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function.
- Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.
- Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination.
- Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9.
- Activates SIRT1 transcription under cellular stress conditions.
- Activates transcription of OSR2.
- Applications:Suitable for use in ELISA, Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:1000-1:5000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
- Specificity：Human, Mouse
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide of human FOXL2
- Shelf Life：1year
- Swiss Prot Number：P58012
- EU Commodity Code：30021010
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