This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins.
EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas.
Its constitutional function is being elucidated.
It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity.
It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas.
It is expressed in undifferentiated pluripotent stem cells.tufting enteropathy.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:5000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Species Crossreactivity: mouse and rat
