84-4264-23　EDNRB 50ul　314390

特徴

• The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system.
• Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3.
• Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
• Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1000-1:2000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.