Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system.
The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development.
Alternative splicing results in multiple transcript variants.
CRMP1 mediates reelin signaling in cortical neuronal migration.
Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.
CRMP1 gene overlaps with another gene called EVC.
CRMP1 has been shown to interact with DPYSL2.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:5000Western Blot: 1:500-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Species Crossreactivity: mouse and rat
