This gene is one of several cytokine genes clustered on the q-arm of chromosome 17.
Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes.
The protein encoded by this gene is structurally related to the CXC subfamily of cytokines.
Members of this subfamily are characterized by two cysteines separated by a single amino acid.
This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils.
It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis.
It binds to chemokine receptors CCR2 and CCR4.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:10,000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
