The predicted AD7CNTP protein contains 375aa and has a calculate molecular mass of about 42kD.
It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions.
AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains.
Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe.
In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.
Applications:Suitable for use in ELISA, Western Blot and Imunohistochemistry.
Other applications not tested.
Recommended Dilutions:ELISA: 1:1000-1:5000Western Blot: 1:200-1:1000Imunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
