Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and ~80 structurally distinct proteins.
This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit.
The protein, which is a functional equivalent of the E.
coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins.
It plays an important role in the elongation step of protein synthesis.
Unlike most ribosomal proteins, which are basic, the encoded protein is acidic.
Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2.
The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer.
The protein is located in the cytoplasm.
Two alternatively spliced transcript variants that encode different proteins have been observed.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Western Blot: 1:200-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity:Recognizes human RPLP1. Species Crossreactivity: mouse and rat