OLFM3 (olfactomedin 3), also known as NOE3, is a 478aa protein that interacts with myocilin.
Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure.
OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an ~260aa motif commonly found in secreted glycoproteins.
OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue.
Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Western Blot: 1:200-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Recognizes human OLFM3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Fusion protein corresponding to human OLFM3.
