The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain.
It is involved in cell adhesion through trans-homophilic and -heterophilic interactions.
It is a single-pass type I membrane protein.
The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE.
The secreted form is found in both breast tumor cell lines and breast tumor patients.
Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:500-1:2000Immunohistochemistry: 1:100-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
