84-4224-06　ACLY 100ul　304433

特徴

• ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.
• The enzyme is a tetramer (relative molecular weight ~440,000) of apparently identical subunits.
• It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate.
• The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
• In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.
• Two transcript variants encoding distinct isoforms have been identified for this gene.
• Applications:Suitable for use in ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.